abstract：:Results of studies that use laboratory tests are often easy to interpret, because we are familiar with the units and how to interpret them. However, this is not the case when the results are presented as ORs, relative risks, correlation, or scores on an unfamiliar scale. This article explains these various indices of ...

journal_title：Chest

authors： Streiner DL,Norman GR

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to compare the safety, use, and cost profiles of open thoracotomy vs video-assisted thoracoscopic surgery (VATS) for wedge resection in lung cancer performed by thoracic surgeons in the United States. METHODS:The Premier database, which contains complete patient billing, hospi...

journal_title：Chest

authors： Howington JA,Gunnarsson CL,Maddaus MA,McKenna RJ,Meyers BF,Miller D,Moore M,Rizzo JA,Swanson S

更新日期：2012-02-01 00:00:00

abstract：:Part 2 of this review of ICU scoring systems examines how scoring system data should be used to assess ICU performance. There often are two different consumers of these data: lCU clinicians and quality leaders who seek to identify opportunities to improve quality of care and operational efficiency, and regulators, pay...

journal_title：Chest

authors： Breslow MJ,Badawi O

更新日期：2012-02-01 00:00:00

abstract：:This article provides the rationale for the approach to making recommendations primarily used in four articles of the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines: orthopedic surgery, nonorthopedic surgery, nonsurgical pat...

journal_title：Chest

authors： Guyatt GH,Eikelboom JW,Gould MK,Garcia DA,Crowther M,Murad MH,Kahn SR,Falck-Ytter Y,Francis CW,Lansberg MG,Akl EA,Hirsh J

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Heparin-induced thrombocytopenia (HIT) is an antibody-mediated adverse drug reaction that can lead to devastating thromboembolic complications, including pulmonary embolism, ischemic limb necrosis necessitating limb amputation, acute myocardial infarction, and stroke. METHODS:The methods of this guideline f...

journal_title：Chest

authors： Linkins LA,Dans AL,Moores LK,Bona R,Davidson BL,Schulman S,Crowther M

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:There are no recommendations on how to measure arm exercise capacity in individuals with COPD. The objectives of this study were (1) to synthesize the literature on measures of arm exercise capacity in individuals with COPD, (2) to describe the psychometric properties and the target construct of each measure...

journal_title：Chest

authors： Janaudis-Ferreira T,Beauchamp MK,Goldstein RS,Brooks D

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Mucosa-associated lymphoid tissue (MALT) lymphoma constitutes approximately 90% of primary pulmonary lymphoma, and the diagnosis of pulmonary MALT lymphoma often requires invasive methods such as surgical lung biopsy. Chromosomal rearrangements involving MALT lymphoma translocation gene 1 (MALT1) have been r...

journal_title：Chest

authors： Kido T,Yatera K,Noguchi S,Sakurai Y,Nagata S,Kozaki M,Tokuyama S,Ogoshi T,Kawanami T,Yoshii C,Mukae H

更新日期：2012-01-01 00:00:00

abstract：:There is increasing clinical, radiologic, and pathologic recognition of the coexistence of emphysema and pulmonary fibrosis in the same patient, resulting in a clinical syndrome known as combined pulmonary fibrosis and emphysema (CPFE) that is characterized by dyspnea, upper-lobe emphysema, lower-lobe fibrosis, and ab...

journal_title：Chest

authors： Jankowich MD,Rounds SIS

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:We sought to determine the efficacy and safety of perioperative treatment with methylprednisolone on the development of lung injury after pulmonary thromboendarterectomy. METHODS:This was a randomized, prospective, double-blind, placebo-controlled study of 98 adult patients with chronic thromboembolic pulmo...

journal_title：Chest

authors： Kerr KM,Auger WR,Marsh JJ,Devendra G,Spragg RG,Kim NH,Channick RN,Jamieson SW,Madani MM,Manecke GR,Roth DM,Shragg GP,Fedullo PF

更新日期：2012-01-01 00:00:00

abstract：:Every country has finite resources that are expended to provide citizens with social "goods," including education, protection, infrastructure, and health care. Rationing-of any resource-refers to distribution of an allotted amount and may involve withholding some goods that would benefit some citizens. Health-care rat...

journal_title：Chest

authors： Evans TW,Nava S,Mata GV,Guidet B,Estenssoro E,Fowler R,Scheunemann LP,White D,Manthous CA

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Self-efficacy explores the emotional functioning and coping skills of an individual and is thought to be a strong predictor of health behaviors, which is particularly important for pulmonary rehabilitation (PR). However, to our knowledge, there is no measure of self-efficacy developed to explore behavior cha...

journal_title：Chest

authors： Vincent E,Sewell L,Wagg K,Deacon S,Williams J,Singh S

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The objective of this study was to systematically review and quantitatively synthesize all randomized controlled trials (RCTs), comparing important outcomes in ventilated critically ill patients who received an early or late tracheotomy. METHODS:A systematic literature search of PubMed, Cumulative Index to ...

journal_title：Chest

authors： Wang F,Wu Y,Bo L,Lou J,Zhu J,Chen F,Li J,Deng X

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Patients with common variable immunodeficiency (CVID) suffer from respiratory infections leading over time to permanent lung damage. Increased radiosensitivity has been described, and clinicians should consider a risk-benefit assessment when ordering a CT scan, in that the exact level of "safe" radiation exp...

journal_title：Chest

authors： Serra G,Milito C,Mitrevski M,Granata G,Martini H,Pesce AM,Sfika I,Bonanni L,Catalano C,Fraioli F,Quinti I

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Previous studies have shown a high prevalence of bronchiectasis in patients with moderate to severe COPD. However, the factors associated with bronchiectasis remain unknown in these patients. The objective of this study is to identify the factors associated with bronchiectasis in patients with moderate to se...

journal_title：Chest

authors： Martínez-García MÁ,Soler-Cataluña JJ,Donat Sanz Y,Catalán Serra P,Agramunt Lerma M,Ballestín Vicente J,Perpiñá-Tordera M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Asthma may increase the risk of comorbid depressive disorders in children. Children suffering from asthma or depression are more often overweight. We examined whether depression was more likely in children with atopic and nonatopic asthma, independent of abdominal adiposity. METHODS:A cross-sectional analys...

journal_title：Chest

authors： Bahreinian S,Ball GDC,Colman I,Becker AB,Kozyrskyj AL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Clinicians lack a validated tool for risk stratification in acute exacerbations of COPD (AECOPD). We sought to validate the BAP-65 (elevated BUN, altered mental status, pulse > 109 beats/min, age > 65 years) score for this purpose. METHODS:We analyzed 34,699 admissions to 177 US hospitals (2007) with either...

journal_title：Chest

authors： Shorr AF,Sun X,Johannes RS,Yaitanes A,Tabak YP

更新日期：2011-11-01 00:00:00

abstract：:Negative pressure pulmonary edema (NPPE) is an important cause of noncardiogenic pulmonary edema but is rarely reported in the setting of bronchospasm. A 43-year-old woman with severe reactive airway disease suffered an episode of severe bronchospasm after endotracheal extubation following an otherwise uneventful gene...

journal_title：Chest

authors： Krodel DJ,Bittner EA,Abdulnour RE,Brown RH,Eikermann M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Tobacco smoke is a major risk factor in the development of COPD. Secondhand smoke (SHS) exposure is a known risk factor in asthma, bronchitis, and coronary artery disease. Elastin is a recognized target for injury in COPD, and the amino acids desmosine and isodesmosine (D/I), which are specific for elastin d...

journal_title：Chest

authors： Slowik N,Ma S,He J,Lin YY,Soldin OP,Robbins RA,Turino GM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Pathogenic bacteria colonize the airways of 30% to 40% of patients with COPD and cause approximately 50% of exacerbations. New strains of nontypeable Haemophilus influenzae (NTHI) and Moraxella catarrhalis are associated with exacerbations. Antimicrobial protein/peptides (AMPs) play important roles in innate...

journal_title：Chest

authors： Parameswaran GI,Sethi S,Murphy TF

更新日期：2011-09-01 00:00:00

abstract：:Macrophages are the most abundant immune cell population in normal lung tissue and serve critical roles in innate and adaptive immune responses as well as the development of inflammatory airway disease. Studies in a mouse model of chronic obstructive lung disease and translational studies of humans with asthma and COP...

journal_title：Chest

authors： Byers DE,Holtzman MJ

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:COPD is a heterogeneous disease characterized by airflow obstruction and diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in phenotyping COPD. However, the use of CT imaging in defining the disease heterogeneity above lung function is not fully known. METHODS:Seventy-five...

journal_title：Chest

authors： Bafadhel M,Umar I,Gupta S,Raj JV,Vara DD,Entwisle JJ,Pavord ID,Brightling CE,Siddiqui S

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The "Dutch hypothesis" suggests that asthma and COPD have common genetic determinants. The serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) gene previously has been associated with COPD. We sought to determine whether SERPINE2 is associated with asthma ...

journal_title：Chest

authors： Himes BE,Klanderman B,Ziniti J,Senter-Sylvia J,Soto-Quiros ME,Avila L,Celedón JC,Lange C,Mariani TJ,Lasky-Su J,Hersh CP,Raby BA,Silverman EK,Weiss ST,DeMeo DL

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is common in patients with cystic fibrosis (CF), and guidelines recommend 25-hydroxyvitamin D (25OHD) levels ≥ 30 ng/mL. This threshold was selected because serum parathyroid hormone (PTH) rises in healthy individuals when the 25OHD level falls below 30 ng/mL. PTH levels > 50 pg/mL are a...

journal_title：Chest

authors： West NE,Lechtzin N,Merlo CA,Turowski JB,Davis ME,Ramsay MZ,Watts SL,Stenner SP,Boyle MP

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Patients with sarcoidosis frequently complain of fatigue, even when sarcoidosis has come into clinical remission. The primary aim of this study was to assess the severity of fatigue in patients with sarcoidosis in clinical remission and to characterize it according to the international criteria for chronic f...

journal_title：Chest

authors： Korenromp IHE,Heijnen CJ,Vogels OJM,van den Bosch JMM,Grutters JC

更新日期：2011-08-01 00:00:00

abstract：:Pulmonary embolism is a common and potentially lethal disease. Given the variable presentation and associated morbidity of this condition, an accurate and efficient diagnostic algorithm is required. Clinical pretest probability serves as the root of any diagnostic approach. We, thus, review several clinical decision r...

journal_title：Chest

authors： Moores LK,King CS,Holley AB

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Asthma therapy is typically prescribed and titrated based on patient or parent self-report of symptoms. No longitudinal studies have assessed the relationship between symptoms and severe asthma exacerbations in children. The goal of our study was (1) to assess the association of asthma symptoms with severe a...

journal_title：Chest

authors： Wu AC,Tantisira K,Li L,Schuemann B,Weiss ST,Fuhlbrigge AL,Childhood Asthma Management Program Research Group.

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:COPD is characterized by chronic airflow limitation and inflammation of the respiratory tract. Several inflammatory biomarkers have been evaluated in COPD but are poorly related to disease severity and progression. Osteoprotegerin (OPG) is a glycoprotein mediator that is expressed in the lung and macrophages...

journal_title：Chest

authors： To M,Ito K,Ausin PM,Kharitonov SA,Barnes PJ

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Pleural effusions frequently accumulate in patients with left-sided heart failure. However, our recent study in patients with idiopathic and heritable pulmonary arterial hypertension (PAH) demonstrated that pleural effusions frequently occur in patients with isolated right-sided heart failure (RHF). The obje...

journal_title：Chest

authors： Luo YF,Robbins IM,Karatas M,Brixey AG,Rice TW,Light RW

更新日期：2011-07-01 00:00:00

abstract：:In most studies, many statistical tests are performed. They can be run to compare the groups at baseline, look at relationships among the various measures, and, for intervention trials, examine more than one end point. As the number of tests increases, so does the probability of finding at least one of them to be stat...

journal_title：Chest

authors： Streiner DL,Norman GR

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:We evaluated the association between hemodynamic parameters of chronic congestive heart failure (CHF) and mediastinal lymphadenopathy (MLA) in heart transplantation (HT) candidates and the effect of HT on MLA. We also described the results of lymph node (LN) biopsies of MLA in the patients. METHODS:Patients...

journal_title：Chest

authors： Pastis NJ Jr,Van Bakel AB,Brand TM,Ravenel JG,Gilbert GE,Silvestri GA,Judson MA

更新日期：2011-06-01 00:00:00

abstract：:Comprehensive pulmonary rehabilitation and respiratory therapy services benefit patients with chronic lung disease and other diseases of the lung by reducing symptoms and restoring independent function. Although the science of these therapies is not new, commercial payers and Medicare have generally been slow to suppo...

journal_title：Chest

authors： Birnbaum S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Current management guidelines for pulmonary arterial hypertension (PAH) recommend a treatment choice based primarily on World Health Organization (WHO) functional class. This study was designed to assess how the incorporation of readily obtained clinical and test-based information may significantly improve t...

journal_title：Chest

authors： Kane GC,Maradit-Kremers H,Slusser JP,Scott CG,Frantz RP,McGoon MD

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Lymph node status is a major determinant of stage and survival in patients with lung cancer; however, little information is available about the expected yield of a mediastinal lymphadenectomy. METHODS:The American College of Surgeons Oncology Group Z0030 prospective, randomized trial of mediastinal lymph no...

journal_title：Chest

authors： Darling GE,Allen MS,Decker PA,Ballman K,Malthaner RA,Inculet RI,Jones DR,McKenna RJ,Landreneau RJ,Putnam JB Jr

更新日期：2011-05-01 00:00:00

abstract：:There is now a new pathway and examination for sleep medicine, sponsored by the American Board of Internal Medicine, and a number of accredited sleep medicine fellowship programs through the Accreditation Council for Graduate Medical Education. This review takes an historical approach to discuss the process of educati...

journal_title：Chest

authors： Strohl KP

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:In adult patients, the consistent use of language to describe dyspnea enhances patient-provider communication and contributes to diagnostic and therapeutic decisions. The objective of this research was to determine whether pediatric patients similarly display consistency in the language used to describe "unc...

journal_title：Chest

authors： Harver A,Schwartzstein RM,Kotses H,Humphries CT,Schmaling KB,Mullin ML

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Stress-induced or tako-tsubo cardiomyopathy (TTC) is a rare acute cardiac syndrome characterized by transient left ventricular (LV) dysfunction of uncertain cause and outcome. This study sought to assess the long-term outcome of patients with TTC. METHODS:One-hundred sixteen consecutive patients were prospe...

journal_title：Chest

authors： Parodi G,Bellandi B,Del Pace S,Barchielli A,Zampini L,Velluzzi S,Carrabba N,Gensini GF,Antoniucci D,Tuscany Registry of Tako-Tsubo Cardiomyopathy.

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Although the physiologic range of pulmonary artery systolic pressure (PASP) has been reported, data on how it is manifested in athletes are limited. The aim of the present study was to explore the full spectrum of PASP and the long-term training impact in a large population of highly trained athletes. METHO...

journal_title：Chest

authors： D'Andrea A,Naeije R,D'Alto M,Argiento P,Golia E,Cocchia R,Riegler L,Scarafile R,Limongelli G,Di Salvo G,Citro R,Caso P,Russo MG,Calabrò R,Bossone E

更新日期：2011-04-01 00:00:00

abstract：:CT scanning allows assessment of airway-wall thickness and is useful for diagnosing and assessing various lung diseases, including asthma and COPD. Several studies have reported that CT scan-estimated dimensions are positively correlated with pulmonary function test results and a positive response to treatment. Howeve...

journal_title：Chest

authors： Hamada S,Ito Y,Imai S,Oguma T,Niimi A,Mishima M

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Communication between families and providers in the ICU affects patient and family outcomes and use of health-care resources. Recent research studies have tested interventions designed to improve communication quality and outcomes between providers and families of patients in the ICU. We conducted a systemat...

journal_title：Chest

authors： Scheunemann LP,McDevitt M,Carson SS,Hanson LC

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:DVT is common among critically ill patients. A rapid and accurate diagnosis is essential for patient care. We assessed the accuracy and timeliness of intensivist-performed compression ultrasonography studies (IP-CUS) for proximal lower extremity DVT (PLEDVT) by comparing results with the formal vascular stud...

journal_title：Chest

authors： Kory PD,Pellecchia CM,Shiloh AL,Mayo PH,DiBello C,Koenig S

更新日期：2011-03-01 00:00:00